Increasing Productivity of Mammalian Cells

CHO Plus is developing engineered mammalian cells with higher specific productivity. Our associated screening technology will yield more high-producing cells while screening fewer clones.
Technology Breakthrough

Using patented and patent-pending methods for creating genetically-engineered cells, CHO Plus has created cells capable of 4.5-fold higher protein productivity in a model system. This will lower production costs, significantly reduce the amount of culture medium required, and reduce the need to build many more expensive manufacturing plants.

 

We are currently working toward demonstration of commercial feasibility via production of Human antibodies.

Relative Specific Productivity
(Percent)
Higher-Productivity Manufacturing Processes

CHO Plus engineered cells currently in commercial feasibility testing could be introduced into existing manufacturing processes and infrastructure. This will dramatically increase production capacity and plant flexibility for existing facilities, and will limit the need for constructing new facilities. Licensing and royalty costs will match accepted industry standards, while providing cell lines with higher productivity.

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